|本期目录/Table of Contents|

[1]王承勇,林 海,王 锦,等.失交感神经支配与新骨形成及改建[J].福建医科大学学报,2014,48(01):29-33.
 WANG Chengyong,LIN Hai,WANG Jin,et al.Effect of Sympathetic Denervation on Bone Formation and Remodeling[J].Journal of Fujian Medical University,2014,48(01):29-33.
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《福建医科大学学报》[ISSN:1672-4194/CN:35-1192/R]

卷:
第48卷
期数:
2014年01期
页码:
29-33
栏目:
论著
出版日期:
2014-12-26

文章信息/Info

Title:
Effect of Sympathetic Denervation on Bone Formation and Remodeling
文章编号:
1672-4194(2014)01-0029-05
作者:
王承勇1 林 海2 王 锦1 危红英3 张德庆4 卢 萌1 陈伟辉1
1.福建医科大学 附属协和医院口腔颌面外科,福建医科大学 牙颌面畸形防治研究室,福州 350001;
2. 厦门市口腔医院 种植科,厦门 361003;
3. 南平市浦城县医院 口腔科,浦城 353400;
4. 龙岩市第二医院 口腔科,龙岩 364000
Author(s):
WANG Chengyong1 LIN Hai2 WANG Jin1 WEI Hongying3 ZHANG Deqing4 LU Meng1 CHEN Weihui1
1. Department of Oral and Maxillofacial Surgery, Oral and Maxillofacial DeformityPrevention Laboratory, Fujian Medical University Union Hospital, Fuzhou 350001, China;
2. Department of Dental Implant, Xiamen Stomatological Hospital, Xiamen 361003, China;
3. Department of Dental, Pucheng Hospital, Pucheng 353400, China;
4. Department of Dental, The Second Hospital of Longyan, Longyan 364000, China
关键词:
大鼠Sprague-Dawley 骨和骨组织 骨生成 骨再生 交感神经系统 染色与标记 拔牙
Keywords:
rats Sprague-Dawley bone and bones osteogenesis bone regeneration sympathetic nervous system staining and labeling tooth extraction
分类号:
R-332; R322.85; R336; R687.3; R782; R782.1
DOI:
-
文献标志码:
A
摘要:
目的探讨交感神经对拔牙窝骨愈合中新骨形成与改建过程的调节作用。 方法 SD大鼠50只,利用颈上神经节切除术建立单侧失交感神经支配大鼠模型,按术后5个时间点(1,3,7,14,21 d)分为5组(n=10),并通过H-E染色技术检测术后各时间点拔牙窝的新生骨量以及新骨组成。 结果 颈上神经节切除术可促进拔牙窝新骨形成,实验组新骨形成明显高于对照组; 且颈上神经节切除术亦可促进新骨改建与成熟,实验组编织骨及板层骨在多个时间点大于对照组。 结论 交感神经在拔牙窝骨愈合期间具有重要的调节作用,失交感神经支配可以促进拔牙窝新骨的形成与骨改建。
Abstract:
Objective To investigate the regular role of sympathetic nerve on bone formation and remodeling during the period of extraction socket healing. Methods Sympathetic denervation model was established by modified unilateral superior cervical ganglionectomy(SCGx)in Sprague-Dawley rats. The neonatal bone mass and composition of new bone in the extraction socket were evaluated by hematoxylin-eosin staining at 1, 3, 7, 14 and 21 days after surgery. Result Compared with the control group, the new bone formation(at 3, 7 and 14 days), woven bone mass(at 3 days)and lamellar bone formation(at 7, 14 and 21 days)was significantly higher in the SCGx group(all P<0.05). Conclusion Sympathetic nerve plays an important regular role in the period of extraction socket healing, and sympathetic denervation promotes the new bone formation and bone remodeling.

参考文献/References:

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备注/Memo

备注/Memo:
收稿日期: 2013-08-30
基金项目: 国家自然科学基金(31070838/C100102); 福建省自然科学基金(2012J06017); 福建省卫生厅青年科研课题(2011-2-8)
作者单位: 1.福建医科大学 附属协和医院口腔颌面外科,福建医科大学 牙颌面畸形防治研究室,福州 350001; 2. 厦门市口腔医院 种植科,厦门 361003; 3. 南平市浦城县医院 口腔科,浦城 353400; 4. 龙岩市第二医院 口腔科,龙岩 364000
作者简介: 王承勇(1980-),男,主治医师,医学硕士
通讯作者: 陈伟辉. Email: dr_whchen@yahoo.com
更新日期/Last Update: 2014-01-31