|本期目录/Table of Contents|

[1]贾新转,魏雅楠,魏兰.不明原因复发性流产患者生化妊娠史与妊娠结局关系的研究[J].福建医科大学学报,2017,51(05):323-325.
 JIA Xinzhuan,WEI Yanan,WEI Lan.Study on the Relationship between Biochemical Pregnancy History and Pregnancy Outcome in URSA Patients[J].Journal of Fujian Medical University,2017,51(05):323-325.
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不明原因复发性流产患者生化妊娠史与妊娠结局关系的研究(PDF)
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《福建医科大学学报》[ISSN:1672-4194/CN:35-1192/R]

卷:
第51卷
期数:
2017年05期
页码:
323-325
栏目:
临床研究
出版日期:
2017-10-30

文章信息/Info

Title:
Study on the Relationship between Biochemical Pregnancy History and Pregnancy Outcome in URSA Patients
文章编号:
16724194(2017)05032303
作者:
贾新转1 魏雅楠1 魏兰2
作者单位: 1.河北医科大学 第四医院生殖医学科,石家庄市050011; 2.河北省胸科医院 胸外科,石家庄市050041
Author(s):
JIA Xinzhuan1 WEI Ya’nan1 WEI Lan2
1. Department of Reproductive Medicine, No.4 Hospital of Hebei Medical University, Shijiazhuang 050011, China; 2. Department of Thoracic Surgery, Hebei Provincial Chest Hospital, Shijiazhuang 050041, China
关键词:
流产习惯性 妊娠并发症 妊娠结局
Keywords:
KEY WORDS:abortion habitual pregnancy complications pregnancy outcomes
分类号:
R322.65; R714.21
DOI:
-
文献标志码:
A
摘要:
目的探讨不明原因复发性流产(URSA)患者的生化妊娠史与妊娠结局的关系。方法选取URSA患者192例,根据既往生化妊娠次数,分为无生化妊娠组(A组)66例,1次生化妊娠组(B组)65例,≥2次生化妊娠组(C组)61例。分析并比较3组患者的临床特征及妊娠结局。结果C组与A组及B组比较,既往自然流产次数(P<0.05)、既往体外受精和胚胎移植自然流产率(P<0.012 5)均显著增高,其自然流产率及自然流产伴正常染色体核型(SANK)率也均显著增高(P<0.012 5)。A组与B组比较,活产率、自然流产率及SANK率差别均无统计学意义(P>0.012 5)。结论≥2次生化妊娠的患者既往复发性流产更为严重,保胎治疗后其活产率较低、自然流产和SANK风险较高。
Abstract:
ABSTRACT:ObjectiveTo investigate the relationship between biochemical pregnancy history and pregnancy outcome in patients with unexplained recurrent spontaneous abortion.MethodsInformation of 192 cases with URSA in our hospital were collected.According to the number of previous biochemical pregnancy, they were divided into non biochemical pregnancy group (group A, 66 cases), one biochemical pregnancy group (group B, 65 cases), and two or more biochemical pregnancy group (group C, 61 cases).The clinical characteristics and the subsequent pregnancy outcome of the three groups were analyzed.ResultsCompared with group A and group B, the number of spontaneous abortion (P<0.05) and the rate of in vitro fertilization and embryo transfer spontaneous abortion (P<0.012 5) in group C were significantly higher.The livebirth was significantly lower in group C than that in group A or in group B (P<0.012 5).The spontaneous abortion rate and the rate of spontaneous abortion with normal karyotype (SANK) in group C were significantly higher than that in group A or in group B (P<0.012 5).Between group A and group B, the livebirth rate, spontaneous abortion rate, and the rate of spontaneous abortion with normal karyotype were not significantly different (P>0.012 5).ConclusionPatients with two or more biochemical pregnancyhad more serious previous recurrent abortion.They had lower livebirth rate, higher spontaneous abortion rate, and higher rate of spontaneous abortion with normal karyotype after preventing miscarriage treatment.

参考文献/References:

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备注/Memo

备注/Memo:
基金项目: 河北省医学科学研究课题计划(20160626) 作者单位: 1.河北医科大学 第四医院生殖医学科,石家庄市050011; 2.河北省胸科医院 胸外科,石家庄市050041 作者简介: 贾新转,女,副主任医师,医学硕士 通讯作者: 魏兰. Email: 1134979643@qq.com
更新日期/Last Update: 2017-10-30