|本期目录/Table of Contents|

[1]柯甦捷,王丽静,齐利琴,等.2型糖尿病患者甲状腺功能与内脏脂肪面积的关系[J].福建医科大学学报,2020,54(02):91-93.
 KE Sujie,WANG Lijing,QI Liqin,et al.Association of Thyroid Function with Visceral FatArea in Type 2 Diabetic Patients[J].Journal of Fujian Medical University,2020,54(02):91-93.
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《福建医科大学学报》[ISSN:1672-4194/CN:35-1192/R]

卷:
第54卷
期数:
2020年02期
页码:
91-93
栏目:
临床研究
出版日期:
2020-04-30

文章信息/Info

Title:
Association of Thyroid Function with Visceral FatArea in Type 2 Diabetic Patients
文章编号:
1672-4194(2020)02-0091-04
作者:
柯甦捷 王丽静 齐利琴 李健榕 刘礼斌
福建医科大学 附属协和医院内分泌科,福州 350001
Author(s):
KE Sujie WANG Lijing QI Liqin LI Jianrong LIU Libin
Department of Endocrinology, Fujian Medical University Union Hospital, Fuzhou 350001, China
关键词:
糖尿病2型 内脏 脂肪类 甲状腺激素类 促甲状腺素
Keywords:
diabetes mellitus type 2 viscera fats thyroid hormones thyrotropin
分类号:
R347; R347.2; R587.1; R977.6
DOI:
-
文献标志码:
A
摘要:
目的 分析2型糖尿病患者甲状腺功能与内脏脂肪面积(VFA)的相关性。 方法 回顾性分析556例2型糖尿病患者的临床资料,依据内脏脂肪面积分为增多组和正常组,收集相关基本信息、血糖、血脂及甲状腺功能指标进行分析。 结果 相关分析显示,甘油三酯(TG)、游离三碘甲状腺原氨酸(fT3)、ln促甲状腺激素(lnTSH)及年龄分别与VFA呈正相关,糖化血红蛋白(HbA1c)、高密度脂蛋白胆固醇(HDL-C)及游离甲状腺素(fT4)分别与VFA呈负相关(P<0.05)。回归分析显示,fT3,lnTSH,TG及年龄是内脏脂肪增多的危险因素(P<0.05)。 结论 在无显性甲状腺功能亢进或减退症及既往无其他甲状腺疾病史的2型糖尿病患者中,除了年龄及TG水平外,甲状腺功能中的fT3及TSH水平升高是内脏脂肪增多的危险因素,提示甲状腺功能状态可能与内脏脂肪堆积密切相关。
Abstract:
Objective To analyze the correlation between thyroid function and visceral fat area(VFA)in type 2 diabetic patients. Methods A retrospective analysis of type 2 diabetic patients managed by the Metabolic Management Center of Fujian Medical University Union Hospital from February 2018 to May 2019 was divided into visceral adipose tissue(VAT)accumulation group and VAT normal group according to VFA. General information, blood glucose, serum lipids profile, and serum thyroid function indicators were collected and analyzed. Results Spearman correlation analysis showed that TG, fT3, lnTSH, and age were positively correlated with VAT area, while HbA1c, HDL-C, and fT4 were negatively correlated with VAT area(P<0.05). Regression analysis showed that fT3, lnTSH, TG, and age were risk factors for VAT accumulation(P<0.05). Conclusion In patients with type 2 diabetes who have no overt hyperthyroidism/ hypothyroidism and no previous history of other thyroid disease, elevated serum circulating fT3 concentration and TSH level are risk factors for VAT accumulation in addition to age and serum triglyceride levels, suggesting that thyroid function status may be closely related to visceral fat accumulation.

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备注/Memo

备注/Memo:
收稿日期: 2019-07-25基金项目: 福建省卫生与计划生育委员会青年课题(2013-2-28); 福建省财政专项经费(2016B019; 2016B020)作者简介: 柯甦捷,女,住院医师,医学博士通讯作者: 刘礼斌. Email: libinliu@fjmu.edu.cn
更新日期/Last Update: 2020-04-30